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The four meta-analyses 134,135,136,137 were successively updated to incorporate upcoming trials, so that the most recent 134 included seven RCTs 138,139,140,141,142,143,144
GLP-1 is a hormone in the body that gets released in response to food intake and helps regulate blood sugar levels
Additionally, they slow gastric emptying from the stomach to the small intestine, promoting satiety more quickly and for longer
Prescription injectable (GLP-1 + GIP receptor agonist) Tirzepatide 22.5% of body weight in 72 weeks (1 year, 5 months) * 2.5mg 5mg 7.5mg 10mg 12.5mg 15mg Once weekly subcutaneous injection (KwikPen) 1 KwikPen (4 doses) - 1 month supply * *SURMOUNT-1, 72-week study of adults with obesity using Zepbound (tirzepatide 15mg)
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