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If your genetic profile shows strong GLP-1 and GIP sensitivity, compounded tirzepatide is likely optimal for you, reinforcing the decision to remain on your current protocol
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Contributing writer MacKenzie Isaac explains SDOH further in this TNG post
If the primary outcome showed superiority, secondary outcomes were tested in a pre-specified order to control the type I errors Total eGFR slope (the annual rate of change in eGFR from randomization to the end of the trial) Major cardiovascular events (a composite of nonfatal MI, nonfatal stroke, or death from CV causes) Death from any cause The other supportive secondary outcomes are shown in the figure below
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