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Rapamycin What It Does: Rapamycin is a powerful mTOR inhibitor that activates the same longevity pathways triggered by caloric restrictionwithout actually restricting calories
(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature
doi:10.2337/dc11-s231 120
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