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A synthetic small molecule, 5-Amino-1MQ isnt body-produced
HCl is responsible for the initial degradation of ingested protein into smaller proteins and protein fragments
[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
Problems with intrinsic factor binding to ileal receptors in the diseased tissue leads to B12 deficiency
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