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An intramolecular disulfide bridge in the receptor-binding domain of the SARS-CoV-2 spike protein between Cys-488 and Cys-480, considered to be important for ACE2-binding, results directly inhibited by NAC and GSH and these compounds could be used effectively against SARS-CoV-2 cell viral entry and infection (Murae et al., 2022)
20 dicembre 2021 [citato 30 giugno 2024];111:110388
It was first described by Raun and colleagues in 1998 and studied in the laboratory for the ghrelin-receptor pathway
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