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L-Carnitine is essential for transporting long-chain fatty acids into mitochondria for conversion into usable energy
That dose, adjusted for human weight, would be roughly 1,600 mg for an average adult, far exceeding any practical use by orders of magnitude
However, a recent meta-analysis of 14 randomized, placebo-controlled trials in 2,149 participants with heart failure found that supplemental coenzyme Q 10 (30-300 mg/day) resulted in a 39% reduction in mortality (seven studies), improved exercise capacity (four studies), but had no effect on left ventricular ejection fraction (nine studies) compared to placebo (34)
/ The liver and kidneys need water to process and excrete metabolic byproducts
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