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I take a little comfort that GLP-1 is a naturally occurring hormone, although we are giving it as a peptide and now as a small molecule orally, so it's not a compound that's foreign to the body, although at higher doses in individuals
For diabetes management, tirzepatide is indicated as an adjunct to diet and exercise to improve glycemic control in adults
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In February of 2025, the FDA declared a shortage of GLP-1 semaglutide, the active ingredient in Ozempic and Wegovy
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