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The FDA is now conducting an investigation into these allegations (1, 3)

Here, we discovered that prolonged treatment of colon cancer cells with IGF-1R inhibitors (BMS-754807 and GSK1838705A) stimulates p70 KDa ribosomal protein S6 kinase 1 (p70S6K1) activation, a well-known kinase signaling for cell survival

It is not licensed as a lipid-lowering medication, and patients requiring pharmacological cholesterol management should continue statins as recommended by NICE guidance, even whilst taking Saxenda for weight loss

This means they produce very powerful, long-lasting effects on appetite suppression, gastric emptying, insulin secretion and weight lossmuch stronger than the natural GLP-1 hormone produced by the body