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The reaction mixture was quenched and precipitated by a 1:1 hexane and ethyl ether solution

This subset of particle projections was subjected to a round of 3D classification resulting in one well-defined subset with 296,989 projections

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A post-hoc analysis of the SURPASS-3 trial in patients with type 2 diabetes showed that tirzepatide reduced liver fat content measured by MRI-PDFF, with significant improvements across all doses compared to insulin degludec