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White/pale patches on skin or mucous membranes, often on hands, face and feet Hair whitening premature greying of scalp, brows, lashes or beard in patches Spread pattern patches may stay localised or spread slowly and unpredictably Usually painless occasionally mild itching precedes a new patch
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Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified
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