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Unlike current GLP-1 treatments, Retatrutide targets three hormone receptors glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon which together may support reduced appetite, slower digestion, improved glucose control and increased energy use

Naunyn Schmiedebergs Arch Pharmacol 379:349359 Gergs U, Fahrion CM, Bock P, Fischer M, Wache H, Hauptmann S, Schmitz W, Neumann J (2017) Evidence for a functional role of calsequestrin 2 in mouse atrium

These are perfectly reasonable options

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