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Bahr, who is prediabetic and has several other health conditions, said she was initially hesitant to use a weight-loss drug because she didn't want to be seen as "taking the easy way out" and was worried about potential side effects

Practical counselling points The oral formulation introduces administration requirements that differ meaningfully from the injectable, and these should form a core part of counselling for anyone switching: The tablet must be taken on an empty stomach, first thing in the morning (minimum 8 hours of fasting), with no more than a small glass (up to 120ml) of plain water

Physiol Behav 257:113967 Masaki T et al (2022) Glucagon-like peptide-1 receptor agonist semaglutide improves eating behavior and glycemic control in japanese obese type 2 diabetic patients

Getting to the brain Trapp is working to fully understand how GLP-1 drugs work is still ongoing, particularly whether these peptide molecules penetrate the brain