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Insulin release is proportional to blood glucose levels

For patients with type 2 diabetes and ASCVD, starting a GLP-1 RA carries a Class 1, Level of Evidence A recommendation in the most recent ESC and ACC guidelines

Although some of these drugs have been prescribed since 2017, their popularity seems to have exploded in the last year, thanks to their use by celebrities, earning them the nickname the Hollywood drug. The social media visibility of these drugs and their remarkable effects on weight loss has led to demand far greater than supply, leading to shortages and an obsession with accessing these precious injections

Combining GLP-1 microdosing with other anti-inflammatory strategies GLP-1 microdosing does not operate in a vacuum