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[3] Other common adverse effects reported during the clinical trials include back pain, upper respiratory tract infections, melanocyte naevus, decreased appetite, migraine, dizziness, weakness, fatigue, lethargy, sleepiness, hot flashes, abdominal pain, diarrhea, vomiting, flushing, development of warts, spots, and freckles, and itchy skin (between 1% and 10% of people)

While about half of all skin-based melanomas have a BRAF mutation , the same mutation only appears in about 15% to 20% of acral lentiginous melanomas

Presented for research literature review only Dzherieva IS et al

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