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1, May 2019, p

Presented for research literature review only Yeates RA et al

"Glutathione is a tiny molecule your body makes in every cell, built from just three amino acids, and it quietly does three jobs at once: it calms the damage that ages you from the inside, it powers your liver's natural detox, and it keeps your whole antioxidant defense running around the clock," she says

This resistance mechanism has been observed in both laboratory-generated resistant strains and clinical isolates, underscoring its relevance in both experimental and field settings (Pountain et al., 2019).The altered sterol profile, often featuring ergosta-7,22-dienol or cholesta-5,7,22-trienol, compromises the drugs efficacy, indicating that mutations in sterol metabolism are central to AmB resistance in Leishmania (Yao and Wilson, 2016