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Although BPC-157 has been proven safe and well-tolerated in clinical trials, there are potential risks such as allergic reactions, interactions with other medications, and unknown long-term effects

Mutations in the Casitas B-cell lymphoma (Cbl)-binding domain are demonstrated to be oncogenic because binding of Cbl to Y1003 causes Met ubiquitination that is vital to maintenance of physiological Met activation and prevention of continued activation of Met (Peschard and Park, 2007)

This favorable safety margin provides reassurance, though extrapolation from animals to humans always involves uncertainty

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