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Doxorubicin was injected after the third measurement (16 minutes) and the resulting changes in PPR and OCR were measured for a further 20 measurements (over 150 minutes) yielding the basal response
These could range from pharmacotherapies targeting specific taste receptors (e.g., TAS2R agonists) to chrono-nutritional strategies and neuromodulation techniques designed to restore healthy signaling in pathological states
Combination therapies (e.g., GLP-1 with GIP or glucagon receptor agonists) and next-generation analogues are being designed to enhance efficacy, tissue targeting, and tolerability
Combining these in balanced meals creates nutritional synergy that supports incretin hormone release
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