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The increase in blood pressure in hyperuricemic individuals is predominantly attributed to oxidative stress and intracellular urate activity, mediated chiefly by xanthine oxidoreductase (XOR)
[25] For ovulation induction in women, a single IM dose of 5,000 to 10,000 IU is administered after follicular maturation, usually 24 to 48 hours before scheduled ovulation or insemination
A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
Understanding the advantages and limitations of each approach helps researchers and patients make informed decisions
