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Furthermore, some animal studies also did not report any change in glutathione content in different tissues (such as the liver, lens and erythrocytes) in riboflavin-deficient animals ( Reference Bates 27 Reference Rao and Bhat 29 )

The peptide is commonly studied in controlled research environments examining biological recovery processes, stress modulation pathways, and nervous-system communication systems

In this regard, to prevent excessive intracellular ROS, cancer cells respond to oxidative stress by inducing the transcription of antioxidant enzymes, highlighting the relevance of an in-depth knowledge of these pathways for use in elaborating therapies that alter ROS levels