Transcellular solute and xenobiotic transport across the BBB is selectively controlled by the local influx and efflux transporters, including ATP-binding cassette (ABC), P-glycoprotein (P-gp, ABCB1), breast cancer resistance protein (ABCG2), multidrug resistance-associated proteins (ABCC) transporters, and solute carrier transporters (Stefano et al., 1995)
E., & Van Gaal, L
Most Americans have some degree of gut compromise from processed food, antibiotic history, chronic stress, or environmental toxins
Diabetes Obes Metab 23(2):508519 Shubrook JH, Radin M, Ali SN, Chubb B, DiPietrantonio K, Collings H, Wyn R, Smith M (2022) Preference for type 2 diabetes therapies in the United States: a discrete choice experiment