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Pancreas 6 (2), 208215
Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-/Smad2/3-mediated epithelial-mesenchymal transition
For the primary endpoint of mean BMI change from baseline, study participants on setmelanotide therapy (n=94) achieved a -15.8% reduction compared with a +2.6% increase among patients on placebo (n=48) at 52 weeks (p 20% of participants) were skin hyperpigmentation, nausea, vomiting and headache
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