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In addition, other relevant therapies based on incretins, including GIP receptor (GIP-R) agonists, dual GLP-1R/GIPR agonists, GLP-1R/GIPR/Glucagon receptor (GCGR) triagonists, and oxyntomodulin (OXM), have been shown to improve outcomes of T2DM in a series of preclinical trials ( Table 1 Characteristics of GLP-1 RAs that have been approved to treat type 2 diabetes as of 2021, modified from Li et al
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Not all users experience this pattern, and some have no muscle pain at any dose
The Link Between GLP-1 Agonists and Gallstone Formation Emerging evidence suggests a potential association between GLP-1 receptor agonist therapy and an increased incidence of gallbladder-related complications, including cholesterol gallstone formation and acute cholecystitis
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