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The GLP-1R is also widely expressed in multiple tissues including several regions of the brain
Changes in thyroid function have been observed in some studies of rapid weight loss, though there is no established causal link between GLP-1 receptor agonists and clinically significant thyroid dysfunction in humans
This pairing is especially relevant for Canadians researching peptide stacks aimed at reducing both scale weight and the metabolically dangerous visceral fat that drives cardiovascular risk
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