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Patients with pre-existing diabetic retinopathy should be monitored carefully, as rapid improvement in blood glucose control may temporarily worsen retinopathy

Obesity is not just a risk factor for other diseases, such as cardiovascular diseases, type 2 diabetes (T2DM), arthritis, and some cancers (6), but also a complex disease with multiple causes, which has its own disabling ability, pathophysiology, and co-morbidities (7)

[16] But thyroid cancer is rare, and the study had some limits, so the results should be read with caution

In addition, higher levels of phosphorylated (active) LKB1 were noted under these conditions in the livers of KO mice but not WT mice (Fig