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NNMT is significantly overexpressed in adipose tissue in obesity and has been identified as a driver of metabolic dysfunction independent of caloric intake
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This binding initiates an intracellular signaling cascade, promoting gene expression related to cell survival, proliferation, and migration, ultimately leading to the formation of new capillary networks and enhanced tissue perfusion
Patients should not take Tranexamic acid if they have a history of venous or arterial clots, actively smoke or are taking oral contraceptive pills
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