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Importantly, an additional experiment showed that LASSS-treated BSA (after the removal of un-reacted LASSS) exhibited nitration resistance to the optimal peroxynitrite-treatment (1:2000 ratio), as shown in supplementary Figure 2, suggesting a model that LASSS-induced chemical modification mechanism exerts a nitration-inhibitory effect on a wide range of proteins susceptible to tyrosine nitration
10.1182/blood-2006-12-027698 84 JangJ
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We additionally highlight emerging peripheral tissue SAAs and the key requirements for reliable clinical use, including sampling, assay standardization, and multicenter validation [13,14,15,16]
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