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Rather than engaging a single high-affinity receptor, the pentadecapeptide modulates multiple intersecting cellular pathways including nitric oxide system signalling, growth-factor receptor expression (notably VEGF receptor 2 and growth-hormone receptor), dopamine and serotonin pathway markers, and angiogenic factor regulation

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However, the absence of solid human clinical trial data means these therapies should be approached with scientific caution and humility

Researchers often turn to synthetic peptides to simulate biological processes, study protein interactions, or develop new therapeutic models