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The planned change, which takes effect Jan
Tirzepatide offers dual agonist activity, targeting both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, which may contribute to its enhanced weight loss efficacy compared to single-receptor agonists
Severe abdominal pain with vomiting : This can be a sign of pancreatitis, listed as a serious risk on the FDA Mounjaro label
Prior studies with the injectable form established cardiovascular benefit, but oral semaglutide had previously demonstrated only cardiovascular safety
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