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doi: 10.17533/udea.rccp.v32n3a01 27 RingseisRKellerJEderK

The acetic acid that is the most abundant in peripheral blood is vital for cholesterol synthesis, a stimulant for adipogenesis via the FFA2 receptor, and a suppressor of appetite via the hypothalamic mechanism

The subsequent development of other GIP/GLP-1 receptor co-agonists confirmed these initial discoveries and the superior action profile of this drug class in obese rodents [85,86,87]