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July 25, 2025
LCMS/MS and pathway analysis LCMS/MS samples were prepared according to a Filter-aided Sample Preparation (FASP) method 69
women comprised 67.6%, and most had dyslipidemia or hypertension at baseline
Even though lower doses are presumably safer, using them would still require a new pre-IND safety justification, dose-range toxicology studies, and possibly a new manufacturing lot release. That would add ~12 years of delay
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