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Description

In the clinical trials of retatrutide, dose escalation was paused or reduced when participants experienced intolerable side effects, most commonly gastrointestinal symptoms such as nausea, vomiting, or diarrhoea

5: 1847 Cederblad G, Lindstedt S

They don't directly target the brain-gut axis the way some IBS-specific medications do, but they support the underlying gut tissue and immune signaling