Ceriello A, Novials A, Canivell S, La Sala L, Pujadas G, Esposito K, Testa R, Bucciarelli L, Rondinelli M, Genovese S: Simultaneous GLP-1 and insulin administration acutely enhances their vasodilatory, antiinflammatory, and antioxidant action in type 2 diabetes
Reverse transcription and quantitative PCR (RT-qPCR) Total RNA was extracted using the RNeasy Mini Extraction kit (74104, Qiagen, Venlo, Netherlands), according to the manufacturers protocol
The underlying genetic defect involves the NF1 tumor suppressor gene, resulting in loss of neurofibromin, a protein responsible for regulating cell growth and preventing uncontrolled cell proliferation
Researchers have widely studied this peptide for its potential role in tissue repair, cellular regeneration, and inflammation control