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AOD-9604 has been tested in over 900 human participants across six randomized, double-blind, placebo-controlled trials
However, this approach has also impacted Type 2 diabetes patients access to GLP-1s by requiring some patients to try other diabetes treatments (e.g., blood sugar regulators such as sodium-glucose cotransporter-2 inhibitor Brenzavvy and dipeptidyl peptidase-4 inhibitor Onglyza) before GLP-1 approval
Legal Basis for the Claims Failure to warn the label and marketing did not adequately disclose the risk of ileus and bowel obstruction Negligent design and testing semaglutide was not adequately evaluated for long-term gastrointestinal safety before release Off-label promotion marketing for weight loss to patients without diabetes, raising informed consent questions Strict product liability the drug was unreasonably dangerous given the warnings provided Note that in California, prescription drug manufacturers are not strictly liable for design defect under Brown v
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