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USA 110 , 1998719994 (2013)

Tirzepatide is a glucagon-like peptide-1 (GLP-1) receptor agonist for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of: 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)

PMID 14578156

Reduced Risk of Chronic Conditions : Obesity is a risk factor for various chronic conditions like diabetes, hypertension, and heart disease, which can exacerbate pain and inflammation