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Published human studies evaluating AOD 9604 primarily used oral doses ranging from 1-5 mg daily
While current research does not show a notable reduction in B12 absorption, the changes in digestion could affect the absorption of nutrients, making it important to take supplements, including vitamin B12
However, when used as part of a wellness or weight loss program, they may be considered elective and require out-of-pocket payment
"Insulin resistance and endothelial function are improved after folate and vitamin B12 therapy in patients with metabolic syndrome: relationship between homocysteine levels and hyperinsulinemia"
