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Oncotarget, 7(36), 5840558417
Across diverse diseases, robust evidence has documented epigenetic modulation of ferroptosis via mechanisms ranging from DNA methylation [130,131,132], histone modifications [133,134,135,136,137], chromatin remodeling [138,139,140,141] to non-coding RNA (ncRNA)-mediated regulation [142,143,144,145,146,147,148,149,150,151,152] (Table 4)
If approved, orforglipron would be the first oral medication that directly competes with injectable GLP-1 therapies on efficacy
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