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The case for priority review: Retatrutide's efficacy (28.328.7% weight loss in its cleanest trials) represents a substantial improvement over the current best-approved option (tirzepatide, 22.5%) arguably a more meaningful leap than tirzepatide represented over semaglutide, which did receive expedited review consideration in some markets

Scientific References TripleHormone-Receptor Agonist Retatrutide for Obesity (Phase 2 Trial)

Wegovy follows a different escalation schedule, starting at 0.25 mg weekly and gradually increasing over 16-20 weeks to the target maintenance dose of 2.4 mg weekly