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Retinol is a well-known ingredient that prevents signs of skin aging
It is synthesized in the liver and kidneys from the amino acids lysine and methionine and is found in nearly all cells of the body
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The pathological hallmark of HD includes intracellular aggregates of mutant huntingtin protein, which have been detected in the blood vessels of the caudate nucleus in HD patients, as well as in the brain tissue of R6/2 mice, a widely used preclinical model of HD [149]
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