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[29, 30, 31] Risk factors: Diabetes (especially in combination with SGLT2 inhibitors use) Reduced oral intake and severe GI symptoms Dehydration Presentation: Nausea, vomiting, abdominal pain Anion gap metabolic acidosis Elevated ketones Normal or mildly elevated glucose Key point: EDKA has not been observed in non-diabetic patients in large cohort data

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Changes in regional body composition over 8 years in a randomized lifestyle trial: the look AHEAD study