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[2] However, elevated MMA is not conclusive, as it is seen in people with B 12 deficiency, but also in elderly people who have renal insufficiency, [28] and elevated homocysteine is not conclusive, as it is also seen in people with folate deficiency
Promotes fat breakdown and inhibits fat storage
The honest boundary is that even the coherent pairing is a mechanistic hypothesis with no human validation, so the most defensible research posture is to study the single compound at its documented dose first, and treat any combination as a further, clearly-labelled research question rather than a default
