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However, if severe vomiting or diarrhea occurs, temporary additional contraceptive methods may be advisable, as with any medication that might cause significant gastrointestinal disturbance
In this model a licensed clinician reviews an intake weight, medical history, and current medications and issues a prescription only when eligibility criteria are met, with follow-up supporting dose titration and side-effect management
Age-related considerations include: Younger adults (18-30) May tolerate dose escalation well but should still follow standard protocols
Why that matters: cortisol and GLP-1 effectiveness are inversely linked, and perimenopausal estrogen decline dysregulates the HPA axis, raising baseline cortisol and driving hormonal belly fat redistribution that keeps women stuck at a normal BMI with real metabolic dysfunction
