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Methods: A comprehensive literature search of PubMed, Cochrane Library, and ClinicalTrials.gov was conducted to identify randomized, placebo-controlled trials (RCTs) evaluating oral semaglutide in T2DM patients aged over 50 years with either CVD or CKD
By lowering fasting and postprandial glucose, tirzepatide helps minimize fluctuations that strain the cardiovascular and metabolic systems
Supports fat and carbohydrate metabolism while facilitating protein synthesis for optimal cellular energy production
In obesity treatment, the hierarchy of outcomes is reversed
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