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Thus, disturbances in mitochondrial ICS biosynthesis could contribute to failures in the supply of energy (which might result in cell death) or to cancer, since genomic instability is considered as a hallmark of cancer and a driver of neoplastic transformation processes
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doi:10.1016/S0140-6736(24)01643-X Perkovic V, Tuttle KR, Rossing P, et al
In patients with refractory IBD, co-administration of anti-TNFs with vedolizumab, ustekinumab or natalizumab has shown promising results in case reports and case series and was not accompanied by a substantial increase in the incidence of serious adverse events, such as serious infections [203]
