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In glucocorticoid-treated rats mimicking osteoporosis, Ipamorelin counteracted steroid-induced bone loss by enhancing bone formation without changing bone mineral density markers
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& Baron-Cohen, S
GLP-1 receptors are expressed on up to 70% cerebral arterioles [18] and endothelial cells, and experimental models demonstrate that GLP-1 signaling promotes arteriolar vasodilation, improved endothelial nitric oxide signaling, and angiogenic pathways such as VEGF upregulation, all of which enhance nutrient and oxygen delivery to metabolically active brain regions [13,14]
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