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A history of serious hypersensitivity to tirzepatide or its excipients is a contraindication to its use, as stated in the FDA prescribing information
2022 AMA CPT Symposium
[2] Anecdotal reports from patients on social media platforms and online forums have mentioned experiencing irritability, mood swings, or emotional changes while taking tirzepatide
Avoid repeated freeze-thaw cycles, as the thermal stress disrupts the peptide chain structure and accelerates degradation
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