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References include the SURMOUNT-1 trial publication (Jastreboff et al., New England Journal of Medicine, 2022), the Mounjaro and Zepbound prescribing information (Eli Lilly, 2024), Liu et al., JAMA Internal Medicine, 2018 (steroid-induced hyperglycemia), and American Diabetes Association Standards of Care, 2024
What often changes after 40 is the physiological environment those medications interact with
Because Retatrutide activates more pathways, early data suggests it may produce greater weight loss results than Semaglutide alone
