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Frequent loss of heterozygosity (LOH) on chromosome 3p in lung tumors was associated with low GPx1 enzyme activities, which may affect the prognosis of lung cancer patients [86]
Across the combined VENTURE study arms, the weekly rate of nausea did not exceed 5% at any point after the first week of treatment
Intra-arterial administration also requires monitoring for thromboembolism and microvascular obstruction [48]
In 2016, concerns regarding retinopathy associated with GLP-1 were first raised in the Semaglutide Unabated Sustainability in Treatment of T2DM (SUSTAIN) 6 trial with semaglutide [89]
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