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The cardiovascular benefits observed with these medications include: Reduction in non-fatal myocardial infarction and stroke Decreased cardiovascular mortality in high-risk populations (demonstrated with liraglutide) Improvements in blood pressure and lipid profiles Weight reduction , which independently lowers cardiovascular risk It is important to distinguish between arterial thrombotic events (such as heart attacks and strokes, which some GLP-1 agonists help prevent) and venous thromboembolism (DVT and PE)

As of March 2026, two trials are actively recruiting new participants: the Maintenance trial (NCT06859268, testing dose reduction after initial weight loss) and a new enrollment trial (NCT07232719, 250 participants with obesity or overweight)

HTMCs were trypsinized and resuspended in culture medium at a density of 2.2 10 6 cells/ml

For example, Novo Nordisk reported Q1 sales growth of about 30 per cent compared with the same period in 2023 for diabetes GLP-1 drugs and about 40 per cent for obesity care drugs