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DPP-4 inhibitors were shown to prevent the inactivation of GLP-1 and GIP resulting in a stimulation of insulin secretion and inhibition of glucagon secretion in a glucose-dependent manner ( Key Development Studies The next step in the path of DPP-4 inhibition to approval for clinical use was the development programs for the DPP-4 inhibitors sitagliptin, vildagliptin, saxagliptin, alogliptin, and linagliptin

The best next step is a personalized consultation with an experienced bariatric team that can review your health history, goals, medication experience, and risk factors