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Engineered as a single-sequence multi-agonist, Retatrutide possesses structural affinity for three distinct metabolic pathways: the Gastric Inhibitory Polypeptide (GIP) receptor, the Glucagon-Like Peptide-1 (GLP-1) receptor, and the Glucagon receptor (GCGR)
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Trends Pharmacol Sci 44(1):50-63
No effects of liraglutide versus placebo on fasting lipids were apparent after 1 year (Figure 4b)
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